BIXEPS UNDERLYING TECHNOLOGY
3 Main Mechanisms
BIXEPS is tuned and optimised to activate the Mitochondria, the "powerhouse" in every cell.
Activated muscles adapt by producing more energy to perform longer and recover stronger.
Activated muscle release Myokines into our blood that regulate other bodily functions like our metabolism, regeneration, and immunity.
Muscle Myokine Medicine
Exercise as Medicine.
Myokines are released during exercise and regulate multiple aspects of our health. Research into the effects of Myokines continues to build.
Learn more about the various effects of Myokines below and how BIXEPS could help.
References: 1. Nieman, D. C., & Wentz, L. M. (2019). The compelling link between physical activity and the body's defense system. Journal of sport and health science, 8(3), 201-217. 2. Gomarasca, M., Banfi, G., & Lombardi, G. (2020). Myokines: The endocrine coupling of skeletal muscle and bone. In Advances in Clinical Chemistry (Vol. 94, pp. 155-218). Elsevier. 3. Hoffmann, C., & Weigert, C. (2017). Skeletal muscle as an endocrine organ: the role of myokines in exercise adaptations. Cold Spring Harbor perspectives in medicine, 7(11), a029793. 4. Jones, A. W., & Davison, G. (2019). Exercise, Immunity, and Illness. In Muscle and Exercise Physiology (pp. 317-344). Academic Press. 5. Lee, J. H., & Jun, H. S. (2019). Role of myokines in regulating skeletal muscle mass and function. Frontiers in physiology, 10. 6. Martinez-Huenchullan, S. F., Tam, C. S., Ban, L. A., Ehrenfeld-Slater, P., Mclennan, S. V., & Twigg, S. M. (2020). Skeletal muscle adiponectin induction in obesity and exercise. Metabolism, 102, 154008. 7. Campbell, K. L., Winters-Stone, K. M., Wiskemann, J., May, A. M., Schwartz, A. L., Courneya, K. S., ... & Morris, G. S. (2019). Exercise guidelines for cancer survivors: consensus statement from international multidisciplinary roundtable. Medicine & Science in Sports & Exercise, 51(11), 2375-2390. 8. Nieman, D. C., & Pence, B. D. (2019). Exercise immunology: Future directions. Journal of Sport and Health Science. 9. Patel, A. V., Friedenreich, C. M., Moore, S. C., Hayes, S. C., Silver, J. K., Campbell, K. L., ... & Denlinger, C. (2019). American College of Sports Medicine roundtable report on physical activity, sedentary behavior, and cancer prevention and control. Medicine & Science in Sports & Exercise, 51(11), 2391-2402. 10. Schmitz, K. H., Campbell, A. M., Stuiver, M. M., Pinto, B. M., Schwartz, A. L., Morris, G. S., ... & Patel, A. V. (2019). Exercise is medicine in oncology: engaging clinicians to help patients move through cancer. CA: a cancer journal for clinicians, 69(6), 468-484. 11. Louzada, R. A. N., Bouviere, J., Matta, L. P., Werneck de Castro, J. P. S., Dupuy, C., de Carvalho, D. P., & Fortunato, R. S. (2020). REDOX SIGNALING IN WIDESPREAD HEALTH BENEFITS OF EXERCISE. Antioxidants and Redox Signaling, (ja). 12. Van Wessel, T., De Haan, A., Van der Laarse, W. J., & Jaspers, R. T. (2010). The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?. European journal of applied physiology, 110(4), 665-694. 13. Wallings, R. L., Herrick, M. K., & Tansey, M. G. (2020). Linking mitochondria to the immune response. Elife, 9. 14. So, B., Kim, H. J., Kim, J., & Song, W. (2014). Exercise-induced myokines in health and metabolic diseases. Integrative medicine research, 3(4), 172-179. 15. Thyfault, J. P., & Bergouignan, A. (2020). Exercise and metabolic health: beyond skeletal muscle. Diabetologia, 1-11.